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商品详细牛津生物医学研究/抗GRP 75 C-末端/试剂盒/GR03
牛津生物医学研究/抗GRP 75 C-末端/试剂盒/GR03
牛津生物医学研究/抗GRP 75 C-末端/试剂盒/GR03
商品编号: GR03
品牌: oxfordbiomed
市场价: ¥5300.00
美元价: 2650.00
产地: 美国(厂家直采)
公司:
产品分类: 计数测量
公司分类: Count_measurement
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Product Overview

A 75 kDa glucose regulated protein (GRP75) is a mitochondrial matrix protein that is generally recognized as a member of the heat shock protein 70 (HSP70) class of proteins. GRP75 is induced under conditions of low glucose and other nutritional and environmental stresses. Closely related proteins have been identified in the immune system (PBP74; CSA), liver (mtHSP70), and cell lines. GRP75 is involved in various chaperoning functions in protein translocation, folding, and function in mitochondria. It also appears to be involved in antigen recognition, cell proliferation, and senescence. Although primarily localized in mitochondria, related forms may be found in cytosol or on the surface of the extracellular membrane.This polyclonal antibody is specific for a peptide corresponding to a carboxy terminal fragment of human GRP75, and has been successfully used for immunoprecipitation, Western blotting, and immunohistochemical detection of GRP75 in human and rodent tissues. This antibody is selective for mature GRP75, and does not cross react with other HSP70 members. 

References:1. Kim, et al., J. Immunol. 154:1614-1623, 1995.2. Wadhwa, Kaul, and Mitsui, Y. Cell Struct. Function, 19:1-10, 1994.3. Webster, et al., DNA and Cell Biol. 13:1213-1220, 1994.4. Mizzen, et al., J. Biol. Chem. 264:20664-20675, 1989
Spec Sheet
GR03_0.pdf
品牌介绍
Oxford Biomedical Research(OBR)公司由Denis M. Callewaert博士于1984年建立。OBR公司开发,生产和销售检测试剂盒,重组蛋白和应用于生物医学和制药研究的抗体,现已具有400多种产品。我们产品的重点是对引发多种疾病的两大风险因素氧化应激和慢性炎症的生物标志物的识别与检测。我们采用专有技术,开发组织和疾病的特异性生物标志物。