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当前位置: 首页 > 产品中心 > Reaction_substrate > 牛津生物医学研究/活性人PAI-1功能检测试剂盒/试剂盒/PI90
商品详细牛津生物医学研究/活性人PAI-1功能检测试剂盒/试剂盒/PI90
牛津生物医学研究/活性人PAI-1功能检测试剂盒/试剂盒/PI90
牛津生物医学研究/活性人PAI-1功能检测试剂盒/试剂盒/PI90
商品编号: PI90
品牌: oxfordbiomed
市场价: ¥10800.00
美元价: 5400.00
产地: 美国(厂家直采)
公司:
产品分类: 反应底物
公司分类: Reaction_substrate
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Product Overview

Background

Plasminogen Activator Inhibitor-1 (PAI-1) is a glycoprotein and member of the serine protease inhibitor (serpin) superfamily. PAI-1 is the primary inhibitor of tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA). This inhibition exhibits antiproteolytic properties that can lead to myocardial infarction, thromboembolic disease with elevated levels of PAI-1. Additionally, PAI-1 is thought to play a role in the function of tissue remodeling and tumor metastasis.

 

 

Assay Principle

This is an ELISA (Enzyme-Linked Immunosorbent Assay) for the quantitative analysis of PAI-1 levels in biological fluid. This PAI-1 test kit operates on the basis of sandwich ELISA where active PAI-1 complexes with uPA and is quantified with the use of an HRP labeled secondary antibody. The functional or active PAI-1 will bind to the uPA coated on the well of the microtiter plate. The latent and complexed forms of PAI-1 will not bind and are discarded at a later washing step. Next, a PAI-1 primary antibody is added to the wells, binding to the captured PAI-1 on the microtiter plate. HRP conjugated secondary antibody is then added for detection of the active PAI-1. Quantitative test results are obtained by the measure and comparison of the sample and standard absorbance readings.human pai-1

 

 

 

 

 

 

MSDS
PI90.MSDS.pdf
Spec Sheet
PI90.pdf
品牌介绍
Oxford Biomedical Research(OBR)公司由Denis M. Callewaert博士于1984年建立。OBR公司开发,生产和销售检测试剂盒,重组蛋白和应用于生物医学和制药研究的抗体,现已具有400多种产品。我们产品的重点是对引发多种疾病的两大风险因素氧化应激和慢性炎症的生物标志物的识别与检测。我们采用专有技术,开发组织和疾病的特异性生物标志物。